Elit: the 80/20 of experiment design

Lorem ipsum dolor sit amet, consectetur adipiscing elit. The two questions: what is the smallest effect that would change what we do, and how long until we can see it?

Sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Everything else — the sequential testing, the variance reduction, the argument about one-sided tests — is downstream of those two answers.

Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat.